Abstract: The traditional way of irrigation and fertilization in blueberry bases not only has a low utilization rate of water and fertilizer, resulting in a large amount of waste and environmental pollution, but also leads to the reduction of the quality of agricultural products, which restricts the healthy development of modern agriculture in China. To solve the above problems, it was used the combination of wireless sensor network monitoring technology and automatic control technology. Based on the blueberry growth environment and the law of water and fertilizer requirements, it was constructed environmental information collection system, intelligent service platform, fertilization system, and environmental control equipment. The system can be real-time monitoring of blueberries growing environment and growth condition. According to the blueberry growth model and precise algorithm, the blueberry greenhouse intelligent water and fertilizer integration system of irrigation, fertilization, and intelligent control of growth and development of blueberry was realized timely and in accordance with the demand. The test results showed that the designed intelligent water and fertilizer integrated system can save 35%-45% of water, 25%-35% of fertilizer, increase blueberry production by 10%-15%, reduce labor by more than 60%, and reduce agricultural pollution when used in blueberry planting.