Abstract: Aiming at the problems such as large energy consumption and environmental pollution in the ordinary coal-fired barn, and a big security risks in biomass fuel baking room, the air source heat pump system was introduced into the ordinary baking room, and the fluid mechanics software FLUENT was used to conduct the numerical simulation of the baking process of different air flow structure, the ground slope structure of the loading chamber and the bottom baffle structure of the heating chamber, so as to obtain the best baking performance of the grill structure. At the same time, the temperature and humidity control system was designed to realize the precise control of the temperature and humidity of the baking room. Finally, the orthogonal experiment of energy saving application effect and temperature and humidity control performance was carried out. The experimental results showed that the energy consumption of the air source heat pump barn designed in this paper was reduced compared with the ordinary coal-fired barn and the biomass fuel barn. The average drying of 1kg tobacco leaves could save 0.77 yuan and 0.35 yuan respectively, and the energy saving and income increase of tobacco farmers were remarkable. The temperature and humidity regulation is more accurate and sensitive, and the baking quality of tobacco leaves is obviously improved.