Abstract: Starting from the background of the rural revitalization of the countryside and the development of the new agricultural sciences in China, based on the practice of the new agricultural science construction practice of local agricultural universities in Jiangsu, through research and literature research methods, analyze the current direction of new agricultural sciences and the results of exploration. Studies have found that agricultural universities in Jiangsu area follow the strategy of rural rejuvenation, combine their own advantages and characteristics, promote the integration of new agricultural sciences and new engineering sciences, and carry out the adjustment and reform of agricultural sciences vertically. Integrate the resources of all parties, promote scientific research innovation and talent training paradigm, multi-disciplinary cross, industry-university-research combination, accelerate the ability to improve the ability of scientific and technological innovation and social services in the agricultural field of universities, promote the high-quality development of higher-quality agricultural education, and comprehensively promote rural revitalization, accelerating the modernization of agricultural and rural areas provides strong talent support and scientific and technological support. The practice exploration of agriculture-related colleges and universities in Jiangsu can provide a reference for the next step in promoting the construction of new agricultural sciences.