Abstract: Salt stress had a critical impact on plant growth and development,including osmotic stress and ion toxicity,which seriously damaged agricultural production and food security.Under salt stress,plant related receptors were stimulated to send Ca²⁺enter the cytoplasmic matrix through the Ca²⁺channels opened on the cell membrane and intracellular calcium storage membrane,resulting in the increase of intracellular Ca²⁺concentration and calcium signal.Ca²⁺,as an important second messenger,transmited signals within and between plant cells,downstream,and caused a series of physiological responses to salt stress at different growth and development stages.Calcium signals mainly included calmodulin（Ca M）,calmodulin like protein（CML）,calcium dependent protein kinase（CDPK）and calcineurin B-like protein（CBL）and CBL interacting protein kinase（CIPK）,and sensed and transmited specific calcium signal information to the downstream,and activated plant physiological response to salt stress.This paper reviewed how plants perceived salt stress stimulation and the mechanism of calcium signal regulation,and looked forward to the problems should be solved in this research field.