Abstract: The changes of photosynthesis,stomatal changes and glandular morphologic of leaves in Glycyrrhiza uralensis were measured with pot-culture drought stress in greenhouse,and the drought resistance of them wereevaluated by membership function and drought resistance coefficient. The response of leaf photosynthesis,stomatalmicromorphology and glandular morphology to drought stress was studied by pot controlled water natural droughtmethod. The results showed that leaf net photosynthetic rate（Pn）,stomatal conductance（Gs）and transpiration rate（Tr）have been rising since the degree of drought resistance after the trend of lower,and the intercellular CO2（Ci）concentration increased rapidly in the severe drought stress. Moreover,leaf total stomata density and stomataopening than with the intensification of the degree of drought stress,the trend of first increases and then decreases,and stomatal opening width is gradually decreasing trend. Importantly,since the degree of drought stress,leafepidermis and lower epidermis gland density overall showed a trend of increase in the total number of gland color asthe degree of drought stress increased gradually deepened,shape appears irregular fold and retraction. Theglandular characteristics on the leaf surface of G. uralensis are involved in the regulation of drought resistance,so asto avoid the damage of drought stress to G. uralensis. Under severe drought stress,stress accelerated theprogrammed death of stomatal cells（PCD）,and G.uralensis seedlings lost their ability to resist drought.