肠道菌群与肠黏膜的互作效应及其机理研究进展

李顺; 袁勇; 黄兴国

doi:10.13881/j.cnki.hljxmsy.2021.01.0038

肠道菌群与肠黏膜的互作效应及其机理研究进展

李顺^1,2,
袁勇^1,2,
黄兴国^1,2,

1. 湖南农业大学动物科学技术学院;
2. 湖南省畜禽安全生产协同创新中心

基金项目:

国家自然科学基金项目(31772617)

长沙市科技计划重大专项(kq1804056)

详细信息

作者简介:
李顺(1996—),男,硕士研究生,研究方向为动物营养与饲料科学,751461541@qq.com

通讯作者:
黄兴国(1969—),男,教授,博士,博士生导师,研究方向为动物营养与饲料科学,2510702848@qq.com

中图分类号: S852.2
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出版历程
- 收稿日期: 2021-01-04
- 刊出日期: 2021-08-09

Research progress on the interaction between intestinal flora and intestinal mucosa and its mechanism

1. College of Animal Science and Technology, Hunan Agricultural University;
2. Hunan Co-Innovation Center of Animal Production Safety

摘要

摘要: 宿主与外界环境的物质交换主要发生在胃肠道,肠黏膜是机体肠道与外界直接接触的第一道屏障,在调节肠道免疫反应和抵御外源病原体入侵等多种生理功能中发挥着至关重要的作用,同时肠道菌群及其代谢物在此过程中也扮演了重要角色。文章对肠道菌群与肠黏膜的互作效应及机理进行了综述,以期为动物肠道相关疾病的治疗提供参考依据。
- 肠道菌群 /
- 肠黏膜屏障 /
- 黏蛋白 /
- 肠上皮细胞 /
- 固有免疫
Abstract: The material exchange between the host and the external environment mainly occurs in the gastrointestinal tracts. Intestinal mucosa is the first barrier between the body’s intestines and the outside environments, and plays a vital role in regulating intestinal immune response, defending the infiltration of foreign pathogens, as well as exerting other physiological functions. Simultaneously, both intestinal flora and its metabolites also play an essential role in these biological events. In this paper, the interaction between intestinal flora and intestinal mucosa and its mechanism were reviewed in order to provide reference for the treatment of animal intestinal diseases.
- intestinal flora /
- intestinal mucosal barrier /
- mucins /
- intestinal epithelial cells /
- innate immunity

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参考文献(54)

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